Andreas Wagner
Table of contents
Research interests
Evolutionary innovation and adaptation in genes, genomes, and molecular networks; genetic robustness and evolvability; evolution by gene duplication; cryptic variation; cooperation and innovation in molecular systems; evolutionary dynamics of transposable elements; conceptual foundations of evolutionary theory; systems biology and evolution of regulatory and signaling circuits
CV
Education and professional positions
| 2011 - present | Professor, Department of Evolutionary Biology and Environmental Studies, University Zurich, Switzerland |
| 2016 - 2020 | Director, Dept. of Evolutionary Biology and Environmental Studies |
| 2021 | Fellow, Stellenbosch Institute for Advanced Study (STIAS), South Africa |
| 2007 - present | Group Leader, Swiss Institute of Bioinformatics |
| 2006 - 2010 | Professor, Department of Biochemistry, University of Zurich, Switzerland |
| 2002 - 2006 | Associate Professor (tenured), Department of Biology, University of New Mexico, USA |
| 2004 - 2005 | Visiting Scientist, Institut des Hautes Études Scientifiques, Bures-sur-Yvette, France |
| 1999 - present | External Professor, The Santa Fe Institute, New Mexico, USA |
| 1998 - 2002 | Assistant Professor, Department of Biology, University of New Mexico, USA |
| 1996 - 1998 | Postdoctoral Fellow, The Santa Fe Institute, New Mexico, USA |
| 1996 | Visiting Scientist, Los Alamos National Laboratory, USA |
| 1995 - 1996 | Fellow, Institute for Advanced Study, Berlin, Germany |
| 1991 - 1995 | Ph.D., Department of Biology, Yale University, USA |
| 1994 | M. Phil., Department of Biology, Yale University, USA |
| 1990 | M.Sc., Department of Molecular Genetics, University of Vienna, Austria |
Selected publications
See complete publication list on Andreas Wagner Lab
- Papkou, A., Garcia-Pastor, L., Escudero, J.A., Wagner, A. (2023) A rugged yet easily navigable fitness landscape of antibiotic resistance. Science 382, eadh3860. DOI: 10.1101/2023.02.27.530293
- Wagner, A. (2023) Evolvability-enhancing mutations in the fitness landscape of an RNA and a protein. Nature Communications 14, 3624. DOI: 10.1038/s41467-023-39321-8
- Karve, S., Dasmeh, P., Zheng, J., Wagner, A. (2022) Low protein expression enhances phenotypic evolvability by intensifying selection on folding stability. Nature Ecology and Evolution 6, 1155—1164. DOI: 10.1038/s41559-022-01797-w
- Toll-Riera, M., Olombrada, M., Castro-Giner, F., Wagner, A. (2022) A limit on the evolutionary rescue of an Antarctic bacterium from rising temperatures. Science Advances 8, eabk3511
DOI: 10.1126/sciadv.abk3511 - Zheng, J., Guo, N., Wagner, A. (2020) Strong selection enhances protein evolvability by increasing mutational robustness and foldability. Science 370, 6521 DOI: 10.1126/science.abb5962
- van Gestel, J., Ackermann, M., Wagner, A. (2019) Microbial life cycles link global modularity in regulation to mosaic evolution. Nature Ecology and Evolution 3, 1184-1196 DOI: 10.1038/s41559-019-0939-6
- Payne, J.L., Wagner, A. (2019) The causes of evolvability and their evolution. Nature Reviews Genetics 20, 24–38. DOI: 10.1038/s41576-018-0069-z
