Homayoun Bagheri

Research Interests

Evolution of multicellularity and differentiation; microbial evolution; evolution of metabolism; population genetics


Education and Professional Positions

2006 - 2012 Assistant Professor, Institute of Evolutionary Biology and Environmental Studies, University of Zurich, Switzerland
2003 - 2006 Postdoctoral Fellow, Max Planck Institute for Infection Biology, Berlin, Germany and Max Planck Institute for Molecular Genetics, Berlin, Germany
2001 - 2003 Postdoctoral Fellow, Santa Fe Institute, Santa Fe, New Mexico, USA
1997 - 2001 Graduate studies (Ph.D.) in Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA
1994 - 1997 Graduate studies (M.Phil.) in Biology, Yale University, New Haven, Connecticut, USA
1989 - 1992 Undergraduate studies (B.Sc.) in Molecular Biology and Biochemistry, University of Wisconsin, Madison, Wisconsin, USA

Selected Publications

  • Schirrmeister BE., de Vos JM., Antonelli A., Bagheri HC. (2013) Evolution of multicellularity coincided with increased diversification of cyanobacteria and the Great Oxidation Event. Proceedings of the National Academy of Sciences, USA, 110: 1791-1796. DOI: 10.1073/pnas.1209927110
  • Dobay A., Gall GEC., Rankin DJ., Bagheri HC. (2013) Renaissance model of an epidemic with quarantine. Journal of Theoretical Biology, 317:348-358. DOI: 10.1016/j.jtbi.2012.10.002
  • Raychaudhuri N., Dubruille R., Orsi GA., Bagheri HC., Loppin B., Lehner CF. (2012) Transgenerational Propagation and Quantitative Maintenance of Paternal Centromeres Depends on Cid/Cenp-A Presence in Drosophila Sperm. PLoS Biology. 10(12): e1001434. Link
  • Schirrmeister BE., Dalquen DA., Anisimova M., Bagheri HC. (2012) Gene copy number variation and its significance in cyanobacterial phylogeny. BMC Microbiology, 12 (1), 177. Link
  • Manser A., Lindholm AK., König B., Bagheri HC. (2012) The effect of polyandry on a distorter system with differential viabilities in the sexes. Communicative & Integrative Biology, 5(6):550-552. DOI: 10.4161/cib.21955
  • Filippini M., Qi W., Jaenicke S., Goesmann A., Smits THM., Bagheri HC. (2012) Genome sequence of the filamentous bacterium Fibrisoma limi BUZ 3T. Journal of Bacteriology, 16(194):4445. DOI: 10.1128/JB.00869-12
  • Rossetti V., Bagheri HC. (2012) Advantages of the division of labour for the long-term population dynamics of cyanobacteria at different latitudes. Proceedings of the Royal Society B: Biological Sciences, 279(1742):3457-3466. DOI: 10.1098/rspb.2012.0755
  • Filippini M., Qi W., Blom J., Goesmann A., Smits T., Bagheri HC. (2012) Genome sequence of Fibrella aestuarina BUZ 2T, a filamentous marine bacterium. Journal of Bacteriology, 194(13):3555. DOI: 10.1128/JB.00550-12
  • Rodrigues J., Rankin DJ., Rossetti V., Wagner A., Bagheri HC. (2012) Differences in cell division rates drive the evolution of terminal differentiation in microbes. PLoS Computational Biology, 8(4). DOI: 10.1371/journal.pcbi.1002468
  • Svercel M., Saladin B., van Moorsel SJ., Wolf S., Bagheri HC. (2011) Antagonistic interactions between filamentous heterotrophs and the cyanobacterium Nostoc muscorum. BMC Research Notes, 4:357. DOI: 10.1186/1756-0500-4-357
  • Schirrmeister BE., Anisimova M., Antonelli A., Bagheri HC. (2011b) Evolution of cyanobacterial morphotypes: taxa required for improved phylogenomic approaches. Communicative and Integrative Biology. 4:424-427. Link
  • Manser A., Lindholm AK., König B., Bagheri HC. (2011) Polyandry and the decrease of a selfish genetic element in a wild house mouse population. Evolution, 65(9): 2435-2447. DOI: 10.1111/j.1558-5646.2011.01336.x
  • Rossetti V., Filippini M., Svercel M., Barbour AD., Bagheri HC. (2011) Emergent multicellular life cycles in filamentous bacteria owing to density-dependent population dynamics. Journal of the Royal Society. Interface, 8(65):1772-1784. DOI: 10.1098/rsif.2011.0102
  • Filippini M., Ortelli C., Svercel M., Bagheri HC. (2011) Interspecies variation in survival and growth of filamentous heterotrophic bacteria in response to UVC radiation. Journal of Photochemistry and Photobiology, B: Biology, 103(3):234-242. DOI: 10.1016/j.jphotobiol.2011.03.018
  • Schirrmeister BE., Antonelli A., Bagheri HC. (2011) The origin of multicellularity in cyanobacteria. BMC Evolutionary Biology, 11(1):45. DOI: 10.1186/1471-2148-11-45
  • Bagheri HC. (2011) Ursprung des Lebens und die Evolution biologischer Organisationsformen. In Reyer, H-U & Schmid-Hempel, P., Darwins Langer Arm - Evolutionstheorie Heute. Vdf Hochschulverlag AG, Zurich. Link
  • Filippini M., Kaech A., Ziegler U., Bagheri HC. (2011) Fibrisoma limi gen. nov., sp. nov., an orange pigmented filamentous bacterium of the family Cytophagaceae isolated from North Sea tidal flats. International Journal of Systematic and Evolutionary Microbiology, 61(6):1418-1424. DOI: 10.1099/ijs.0.025395-0
  • Filippini M., Svercel M., Laczko E., Kaech A., Ziegler U., Bagheri HC. (2011a) Fibrella aestuarina gen. nov., sp. nov., a filamentous bacterium of the family Cytophagaceae isolated from North Sea tidal flats and emended description of the genus Rudanella Weon et al., 2008. International Journal of Systematic and Evolutionary Microbiology, 61: 184-189 DOI: 10.1099/ijs.0.020503-0
  • Rossetti V., Schirrmeister BE., Bernasconi MV., Bagheri HC. (2010) The evolutionary path to terminal differentiation and division of labor in cyanobacteria. Journal of Theoretical Biology, 262: 23-34. DOI: 10.1016/j.jtbi.2009.09.009
  • Bürger R., Bagheri HC. (2008) Dominance and Its Evolution. In: Jorgensen, S E; Fath, B. Encyclopedia of Ecology. Amsterdam: Elsevier, 945-952. DOI: 10.5167/uzh-8584
  • Som C., Bagheri HC., Reyer H-U. (2007) Mutation accumulation and fitness effects in hybridogenetic populations: A comparison to sexual and asexual systems. BMC Evolutionary Biology, 7:80-90. DOI: 10.1186/1471-2148-7-80
  • Bagheri HC. (2006) Unresolved boundaries of evolutionary theory and the question of how inheritance systems evolve: 75 years of debate on the evolution of dominance. J. Exp. Zoology Part B: Molecular and Developmental Evolution, 306(4):329-59. DOI: 10.1002/jez.b.21069
  • Bagheri HC., Wagner GP. (2004) "Evolution of dominance in metabolic pathways." Genetics, 168: 1713-1735. DOI: 10.10.1534/genetics.104.028696
  • de Visser JAGM., Hermisson J., Wagner GP., Meyers LA., Bagheri-Chaichian H., Blanchard JL., Chao L., Cheverud JM., Elena SF., Fontana W., Gibson G., Hansen TF., Krakauer D., Lewontin RC., Ofria C., Rice SH., von Dassow G., Wagner A., Whitlock MC. (2003) Perspective: Evolution and detection of genetic robustness. Evolution, 57(9):1959-72. Link
  • Bagheri-Chaichian H., Hermisson J., Vaisnys J., Wagner GP. (2003) Effects of epistasis on phenotypic robustness in metabolic pathways. Mathematical Biosciences, 184(1):27-51. Link
  • Wagner GP., Laubichler MD., Bagheri-Chaichian H. (1998) Genetic measurement theory of epistatic effects. Genetica, 102/103: 560-580. Link
  • Wagner GP., Booth G., Bagheri-Chaichian H. (1997) A population genetic theory of canalization. Evolution, 51(2):329-347. Link
  • Bagheri-Chaichian H., Wagner GP. (1997) Representational issues in the evolution of physiological adaptations. Issue on biology and philosophy, Eur. J. of Semiotic Studies, 9(2):321-354.