> User's Guide > Flux Balance Analysis > Pathway Identification
MS Network Reduction

This process is used to reduce the size of stoichiometric networks for the purpose of identifying the steady state cycles they contain. The algorithm used was described by Mahadevan and Schilling in 2003 [1]. All reactions in the provided network must be irreversible, or else an error will be reported. The output of this process can be used as input for Extreme Current Identification or as input for Metatool using the Metatool Input File Writer.

References
1. Mahadevan R., Schilling C. H. (2003) The effects of alternate optimal solutions in constraint-based genome-scale metabolic models. Metab. Eng., 5(4): 264-76.

Here is the set of keywords this process understands, along with a description of their possible corresponding values. See the command line documentation for more information about keyword-value pairs.


Required Keywords Possible Values
Process FBA MS Network Reduction
Reaction File The name of an FBA Reaction File containing a stoichiometric network.
Program Solver The name of the program solver to be used during network reduction. See Program Solvers for further information.
Output File Name The name of the file to which the reduced fluxome will be written. See FBA Reaction Files for further information.
Optional Keywords Possible Values
Program Solver Parameter File The name of the file containing parameters for the linear program solver. See Program Solver Parameter Files for further information.

Examples

Click here for an example.