> User's Guide > Flux Balance Analysis > Optimization | ||||||||
FBA Constraint
Variation
This process is used to compute the effects of varying the flux constraints in a stoichiometric network. The following steps are executed during this process:
Note: At the beginning of the process, the first set of flux constraints is considered to be the next set. Here is the set of keywords this process understands, along with a description of their possible corresponding values. |
Required Keywords | Possible Values |
Process | FBA Constraint Variation |
Reaction File | The name of an FBA Reaction File containing a stoichiometric network. |
Constraint Variation File | The name of a text file containing the user-defined flux constraint variations. See Constraint Variation Files for further information. |
Objective Function | The objective function to be optimized for each set of constraints. See Objective Functions for further information. |
Optimization Sense | The sense, or direction, in which the optimal values will be computed. See Optimization Senses for further information. |
Program Solver | The name of the program solver to be used to compute the optimal values. See Program Solvers for further information. |
Output File Name | The name of the file to which the computed values will be written. See FBA Multiple-Optimization Output Files for further information. |
Data Headers | The data headers of the specified output file. See FBA Optimization Data Headers for further information. |
Optional Keywords | Possible Values |
Constraints File | The name of a text file containing an initial set of flux constraints. See Constraints Files for further information. |
Constraint Tolerance | The amount by which the linear program solver is allowed to violate the defined flux constraints. See Constraint Tolerances for further information. |
Safety Level | The safety level at which the optimization will be performed. See Safety Levels for further information. |
Program Solver Parameter File | The name of the file containing parameters for the linear program solver. See Program Solver Parameter Files for further information. |
ExamplesClick here for an example. |