Frédéric Guillaume

Research Interests

Evolutionary quantitative genetics, evolution of pleiotropy, evolution of dispersal, evolution in structured populations, effects of inbreeding, computational evolutionary genetics, evolutionary ecology, eco-evolutionary dynamics and the maintenance of biodiversity.


Education and Professional Positions

2014 - present SNSF Assistant Professor, Department of Evolutionary Biology and Environmental Studies, University of Zurich, Switzerland
2009 - 2013 Ambizione Fellow, Junior Group Leader, Theoretical Biology group, ETH Zurich, Switzerland
2005 - 2009 SNSF Postdoctoral fellow, Department of Zoology, University of British Columbia, Vancouver, Canada
2005 Research Assistant, Department of Ecology and Evolution, University of Lausanne, Switzerland
2001 - 2005 Graduate studies (Ph.D.), Department of Ecology and Evolution, University of Lausanne, Switzerland
2000 - 2001 M.Sc. in Biology, Department of Ecology and Evolution, University of Lausanne, Switzerland
1996 - 2000 Undergraduate studies in Biology, University of Lausanne, Switzerland
1993 - 1996 Undergraduate studies in Environmental Engineering, ETH Lausanne (EPFL), Switzerland

Selected Publications

  • Schmid M, Dallo R, and F Guillaume. 2019. Species' range dynamics affect the evolution of spatial variation in plasticity under environmental change. The American Naturalist 193:00-00. DOI : 10.1086/703171
  • Csilléry K, Rodríguez-Verdugo A, Rellstab C, and F Guillaume. 2018. Detecting the Genomic Signal of Polygenic Adaptation and the Role of Epistasis in Evolution. Molecular Ecology 27:606--612.  DOI: 10.1111/mec.14499
  • Chebib J., Guillaume F. 2017. What affects the predictability of evolutionary constraints using a G-matrix? The relative effects of modular pleiotropy and mutational correlation. Evolution, 71(10):2298-2312.  DOI: 10.1111/evo.13320
  • Schmid M., Guillaume F. 2017. The role of phenotypic plasticity on population differentiation. Heredity, 119(4):214-225. DOI: 10.1038/hdy.2017.36
  • Cotto O., Wessely J., Georges D., Klonner G., Schmid M., Dullinger S., Thuiller W., Guillaume F. 2017. A dynamic eco-evolutionary model predicts slow response of alpine plants to climate warming. Nature Communications, 8:15399. DOI: 10.1038/ncomms15399
  • Gienapp P., Fior S., Guillaume F., Lasky JR., Sork VL., Csilléry K. 2017. Genomic Quantitative Genetics to Study Evolution in the Wild. Trends in Ecology & Evolution, 32(12):897-908. DOI: 10.1016/j.tree.2017.09.004


  • Koch EL, and F Guillaume. 2018. Combining transcriptomic and fitness data reveals additive and mostly adaptive plastic responses of gene expression to multiple stress in Tribolium castaneum. BioRxiv DOI: 10.1101/442145.
  •        Grossen C, Guillaume F, Keller LF, and D Croll. 2019. Accumulation and purging of deleterious mutations through severe bottlenecks in ibex. BioRxiv DOI:10.1101/605147