Frédéric Guillaume

Research Interests

Evolutionary quantitative genetics, evolution of pleiotropy, evolution of dispersal, evolution in structured populations, effects of inbreeding, computational evolutionary genetics, evolutionary ecology, eco-evolutionary dynamics and the maintenance of biodiversity.


Education and Professional Positions

2014 - present SNSF Assistant Professor, Department of Evolutionary Biology and Environmental Studies, University of Zurich, Switzerland
2009 - 2013 Ambizione Fellow, Junior Group Leader, Theoretical Biology group, ETH Zurich, Switzerland
2005 - 2009 SNSF Postdoctoral fellow, Department of Zoology, University of British Columbia, Vancouver, Canada
2005 Research Assistant, Department of Ecology and Evolution, University of Lausanne, Switzerland
2001 - 2005 Graduate studies (Ph.D.), Department of Ecology and Evolution, University of Lausanne, Switzerland
2000 - 2001 M.Sc. in Biology, Department of Ecology and Evolution, University of Lausanne, Switzerland
1996 - 2000 Undergraduate studies in Biology, University of Lausanne, Switzerland
1993 - 1996 Undergraduate studies in Environmental Engineering, ETH Lausanne (EPFL), Switzerland

Selected Publications

  • Chebib J., Guillaume F. (2017) What affects the predictability of evolutionary constraints using a G-matrix? The relative effects of modular pleiotropy and mutational correlation. Evolution DOI: 10.1111/evo.13320
  • Schmid M., Guillaume F. (2017) The role of phenotypic plasticity on population differentiation. Heredity DOI: 10.1038/hdy.2017.36
  • Cotto O., Wessely J., Georges D., Klonner G., Schmid M., Dullinger S., Thuiller W., Guillaume F. (2017) A dynamic eco-evolutionary model predicts slow response of alpine plants to climate warming. Nature Communications, 8, 15399. DOI: 10.1038/ncomms15399
  • Polster R., Petropoulos CJ., Bonhoeffer S., Guillaume F. (2016) Epistasis and pleiotropy affect the modularity of the genotype-phenotype map of drug resistance in HIV-1. Molecular Biology and Evolution 33:3213-3225.  DOI: 10.1093/molbev/msw206
  • Guillaume F., Otto SP. (2012) Gene functional trade-offs and the evolution of pleiotropy. Genetics, 192:1389-1409. DOI: 10.1534/genetics.112.143214
  • Guillaume F. (2011) Migration–induced phenotypic divergence: The migration–selection balance of correlated traits. Evolution 65:1723-1738. DOI: 10.1111/j.1558-5646.2011.01248.x
  • Yeaman S., Guillaume F. (2009) Predicting adaptation under migration load: The role of genetic skew. Evolution 63:2926-2938. DOI: 10.1111/j.1558-5646.2009.00773.x
  • Whitlock MC., Guillaume F. (2009) Testing for spatially-divergent selection: Comparing QST to FST. Genetics 183:1055-1063. DOI: 10.1534/genetics.108.099812